Selected Reaction Monitoring (SRM), Multiple Reaction Monitoring (MRM), and Consecutive Reaction Monitoring (CRM)
نویسندگان
چکیده
منابع مشابه
Protein significance analysis in selected reaction monitoring (SRM) measurements.
Selected reaction monitoring (SRM) is a targeted mass spectrometry technique that provides sensitive and accurate protein detection and quantification in complex biological mixtures. Statistical and computational tools are essential for the design and analysis of SRM experiments, particularly in studies with large sample throughput. Currently, most such tools focus on the selection of optimized...
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Multiple reaction monitoring (MRM) is a mass spectrometry technique based on selection of a peptide ion and one or more characteristic fragment ions. The MRM method has previously been shown to be specific, accurate, and reproducible between laboratories. Through the use of retention time windows, MRM-based quantitation can also be multiplexed to analyze and quantitate hundreds of proteins per ...
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ژورنال
عنوان ژورنال: Journal of the Mass Spectrometry Society of Japan
سال: 2021
ISSN: 1340-8097,1880-4225,1884-3271
DOI: 10.5702/massspec.20-116